ClarioPath™ Assessment Report

The mouth carries a chronic‑cost warning light most health plans can't access.

Nesso Health turns a routine periodontal exam into an early risk signal across eight of the costliest chronic conditions — captured at a visit your population already attends.

Oral Health Exam ClarioPath™ Report Cardiovascular Diabetes Kidney disease Osteoporosis (OP) Dementia Sleep apnea Pregnancy complications Oral cancer
ONE CHAIRSIDE DATA POINT → CLEAR MANAGEMENT AND RISK SIGNALS
$1,548
Saved per member — Kaiser's integrated model
13%
Fewer physician visits, per year
0.4%
A1c drop, like a second drug
Proprietary
Scoring process behind the ClarioPath™ Assessment Report
The gap

Your highest-risk members are already sitting in a dental chair.

Health systems, ACOs, TPAs, and self-insured employers spend heavily on chronic disease management downstream — after the diagnosis, after the ER visit, after the cost has already landed. Periodontal disease is a validated leading indicator for the conditions driving that spend, and it's captured at a visit your population already attends. Today, that data stops at the dental chart. Oral care delivers outsized chronic disease impact. Coordination with medical is what unlocks it.

  • 01 Dental and medical claims are adjudicated separately, so periodontal risk never reaches a care manager.
  • 02 Chronic disease programs enroll members after a diagnosis, not before one.
  • 03 Employers and TPAs pay for both dental benefits and chronic disease spend without connecting the two.
  • 04 Dentists are trained to see the signal, but have no structured way to route it to the people who manage the risk.
  • 05 Only a select group of dentists take vitals that provide critical information for chronic disease identification and management.
How it works

From chairside exam to a routed risk score.

The ClarioPath™ Assessment Report was built to fit inside a workflow that already exists, not replace it.

STEP 01

Capture at the chair

Periodontal disease scores combined with vitals and health history collected during a routine exam are submitted from the dental practice — no extra visit, no extra device.

STEP 02

Score across 8 conditions

The ClarioPath™ Assessment Report converts periodontal findings into management and risk scores for cardiovascular disease, diabetes, kidney disease, osteoporosis (OP), dementia, sleep apnea, pregnancy complications, and oral cancer.

STEP 03

Route to care management

Elevated-risk scores are routed to the health plan, ACO, or care management team already responsible for that member — early enough to act on it.

What the Patient and Care Team Receives

Not a referral. A clinical trigger.

Not a cleaning receipt. A scored, banded assessment written for the patient and the physician — with the chairside findings that produced it, an interpretation, and a recommendation the care team can act on.

Every element below comes from a single routine dental encounter. No new tests, no new site of care, no additional visit.

ClarioPath™ Assessment Report De-Identified Sample
PT-4471Age 66MEncounter: Periodontal Maintenance
Diabetes Management Score
6.4/ 10
Low RiskHigh Risk
Moderate Risk
“Rapidly progressing periodontitis often contributes to insulin resistance. A1c may rise without periodontal control.”
Captured Chairside
Glucose 174 mg/dL BP 140/90 · Stage 2 HTN Periodontitis Stage II, Grade C Current smoker Report flag: HIGH PRIORITY
Full Risk Panel — Same Encounter
Cardiovascular disease1.8×Elevated
Kidney disease1.9×Elevated
Sleep apnea8.0 / 10Elevated
Dementia1.8×Monitor
Osteoporosis1.3×Baseline
Oral cancer screeningNegativeClear
Recommendation & Routing

Intensive periodontal therapy with medical coordination. Report transmitted to the attributed primary care team as a documented clinical trigger — supporting HbA1c and blood pressure care gap closure, and available to the Annual Wellness Visit and Chronic Care Management workflow.

De-identified sample report. Not a patient record. ClarioPath™ scores are decision-support tools, not a diagnosis; all findings require physician confirmation.

Eight conditions, one signal

Built on the conditions that drive your medical spend.

Each condition below has a documented periodontal-disease correlation. The ClarioPath™ assessment scores risk across all eight from a single exam.

01

Cardiovascular disease

Inflammatory pathway linked to atherosclerosis and cardiac events.

02

Diabetes

Bidirectional relationship with glycemic control and complication risk.

03

Kidney disease

Periodontal inflammation associated with declining renal function.

04

Osteoporosis (OP)

Periodontal bone loss tracks with systemic bone density decline.

05

Dementia

Chronic oral inflammation is associated with elevated cognitive decline risk.

06

Sleep apnea

Airway and oral structure findings surface undiagnosed cases.

07

Pregnancy complications

Associated with preterm birth and low birth weight risk.

08

Oral cancer

Direct screening opportunity at the source of the exam.

Evidence, not a pitch

Grounded in a peer-reviewed foundation.

The ClarioPath™ Assessment Report builds on published, actuarial-grade research — not a theory of what dental data might predict.

“Oral diseases are interconnected with major noncommunicable diseases (NCDs), sharing common risk factors. Poor oral health is linked to cardiovascular diseases, diabetes, cancers, and chronic respiratory diseases.”
World Health Organization, 2022
The foundation

This is not a single study or an emerging hypothesis. More than 50 cohort studies covering over 4 million patients link periodontal disease to cardiovascular disease, stroke, and diabetes — and that count is conservative. At the umbrella level, 293 systematic reviews spanning 855 meta-analytic comparisons across 28 noncommunicable diseases have examined the oral–systemic relationship, with 41 systematic reviews and 839 primary studies on cardiovascular disease alone. The ClarioPath™ Assessment Report operationalizes that body of evidence into a routable risk signal.

4.4M+
Patients in the pooled cardiovascular and diabetes cohort literature
293
Systematic reviews with meta-analysis across 28 noncommunicable diseases
Cochrane
Moderate-certainty evidence: HbA1c −0.4% from periodontal therapy
Guo X, et al. PLOS ONE 2023;18(9):e0290545 (39 cohorts, 4,389,263 patients) · Stöhr J, et al. Scientific Reports 2021;11:13686 (15 cohorts) · Botelho J, et al. Nature Communications 2022;13:7614 (umbrella review, 293 systematic reviews) · Arbildo-Vega HI, et al. BMC Oral Health 2024;24:1308 (41 reviews, 839 primary studies) · Simpson TC, et al. Cochrane Database of Systematic Reviews 2022;4:CD004714 (35 RCTs, 3,249 patients) · Jeffcoat MK, et al. American Journal of Preventive Medicine 2014;47(2):166–174 (338,891 members). Association evidence establishes periodontal status as a population risk marker; Nesso Health is developing proprietary implementation outcome data through its pilot program.
Who we serve

Built for the organizations that own the cost of chronic disease.

Close the medical-dental gap in your risk models.

Health systems and ACOs carry downside risk on the same chronic conditions periodontal disease predicts. The ClarioPath™ Assessment Report gives your population health team a validated, early risk signal from a visit type your risk-adjustment models currently treat as invisible.

20–40%
Of patients with periodontal disease screened at the chair have undiagnosed diabetes or prediabetes — EFP/IDF consensus

No new benefit. No new vendor. A cost lever you already fund.

You are already paying for dental. You are already paying for chronic disease claims. They are adjudicated as separate line items by different administrators, so the risk signal sitting in one never reaches the team managing the other. ClarioPath™ routes it — into the disease management and stop-loss strategy you already run, with nothing new for members to enroll in, learn, or be sold on. The spend is committed either way. The only question is whether you get the medical value out of it.

$1,548
Saved per member annually — Kaiser Permanente integrated care model

The physical touchpoint your model can't reach through a screen.

Virtual-first care has one structural limit: nobody takes a blood pressure over video. Your members sit in a dental chair on a recall schedule anyway — examined in person, vitals in hand, by a clinician they already trust. ClarioPath™ captures that encounter and routes it to you: real vitals, a periodontal risk score, and members surfaced before a diagnosis triggers enrollment. It is added exposure to the patient, on a cadence you don't have to create, with no new outreach competing for their attention.

2× / year
Recurring in-person touchpoints with members your platform reaches only by screen

Know which pregnancies to watch, earlier.

A single NICU admission averages $71,158 in employer-sponsored plans, and 18% of newborns need some level of NICU care. Your entire model depends on identifying the pregnancies headed there before they get there. Periodontal disease is a validated marker for exactly that population — associated with 2.2× the odds of preeclampsia and 1.6× the risk of preterm birth. ClarioPath™ turns a routine dental exam into an early stratification signal, so your care team knows where to concentrate before the second trimester.

2.2×
Preeclampsia odds in women with periodontal disease — pooled across 23 systematic reviews
The new standard of care

Two patients. Same exam. Very different visit.

Every dentist is trained to recognize the signs. What separates a Nesso Health provider is what happens next.

A routine dental visit

The finding stops at the chart.

  • Periodontal probing performed and charted as a dental problem.
  • No vitals taken. No blood pressure, no current medication reconciliation.
  • Health history collected once at intake and rarely revisited.
  • Referrals go to other dentists. The patient's physician is never contacted.
  • The patient is told to floss more. The only paperwork received is the bill.
A Nesso Health Visit

The finding becomes clinical intelligence.

  • 01Periodontal scores captured alongside vitals and a current health history — the way a medical encounter is documented.
  • 02Findings scored against eight chronic conditions, not filed as an isolated dental issue.
  • 03Disease management and elevated risk scores are routed to the physician or care team responsible for that patient, in a form their system can use.
  • 04Undiagnosed disease gets surfaced — 20–40% of periodontal patients screened have undiagnosed diabetes or prediabetes.
  • 05Similar to a physician visit summary, the patient leaves with a report — understanding the impact their oral health has on the rest of their body.

The signal is already in your data. Let's prove it.